Description

n-Acetyl-N,o-Bis(tert-Butoxycarbonyl) Serotonin is a key protected derivative of the essential neurotransmitter serotonin, designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring a stable, reactive intermediate for the controlled synthesis of complex bioactive molecules. It is primarily utilized in pharmaceutical R&D and fine chemical synthesis for developing novel therapeutic agents targeting neurological and psychiatric conditions.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel serotonin receptor agonists, antagonists, and other central nervous system (CNS) active compounds.
• Peptide and Conjugate Synthesis: Used to incorporate modified serotonin moieties into peptides, drug conjugates, or bioconjugates for targeted drug delivery and research.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by allowing selective deprotection and functionalization of the serotonin backbone.
• Chemical Biology Probes: Serves as a precursor for developing fluorescent, affinity, or photoaffinity labels to study serotonin pathways and receptor interactions.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs) under controlled, protected conditions.

Basic Information

Product Name	n-Acetyl-N,o-Bis(tert-Butoxycarbonyl) Serotonin
CAS No.	1329474-59-0
Molecular Formula	C23H32N2O7
Molecular Weight	448.51 g/mol
Synonyms	5-HT-Boc2-Ac; N-Acetyl-O,N-Bis-Boc-serotonin; Serotonin, N-acetyl-, N,O-bis(1,1-dimethylethyl) ester; 5-Hydroxytryptamine, N-acetyl-, N,O-bis(tert-butoxycarbonyl) derivative; N-Acetylserotonin N,O-bis(tert-butyl carbonate); N-ACETYL-N,O-BIS(tert-BUTOXYCARBONYL)-5-HYDROXYTRYPTAMINE; 2-((tert-Butoxycarbonyl)(2-(5-((tert-butoxycarbonyl)oxy)-1H-indol-3-yl)ethyl)amino)ethyl acetate
EINECS	Contact for details

Quality Control

Our n-Acetyl-N,o-Bis(tert-Butoxycarbonyl) Serotonin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as specified on the label or COA. The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.