Description

3-Bromo-5-Chlorothieno[2,3-C]Pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused-ring structure, incorporating bromine and chlorine substituents, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Serves as a versatile building block for creating new herbicides, fungicides, and insecticides with potentially improved efficacy and selectivity.
• Material Science Research: Used in the development of organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs), due to its electron-rich thienopyridine core.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Cross-Coupling Reactions: The bromine and chlorine atoms provide distinct sites for sequential palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), enabling rapid diversification.
• Ligand Precursor: Can be functionalized to create novel ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Bromo-5-Chlorothieno[2,3-C]Pyridine
CAS No.	1326715-11-0
Molecular Formula	C7H3BrClNS
Molecular Weight	248.53 g/mol
Synonyms	3-Bromo-5-chlorothieno[2,3-c]pyridine; Thieno[2,3-c]pyridine, 3-bromo-5-chloro-; 5-Chloro-3-bromothieno[2,3-c]pyridine; 3-Bromo-5-chloro-4-azathianaphthene; 3-Br-5-Cl-thieno[2,3-c]pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Chlorothieno[2,3-C]Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.