Description

(2S)-trans-7-Chloro-2′,4,6-Trimethoxy-6′-Methylspiro(Benzofuran-2[3H],1′-[2]Cyclohexene)-3,4′-Dione-13C17 Solution is a high-purity, stable-isotope labeled compound designed for advanced analytical and research applications. This product is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in pharmacokinetic and metabolic studies where precise internal standards are required. It is an essential material for pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in method development and validation using mass spectrometry.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative internal standard in Liquid Chromatography-Tandem Mass Spectrometry for the accurate measurement of its unlabeled counterpart or related metabolites.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and stability testing.
• Clinical Research: Enables precise quantification in human and animal plasma, serum, or tissue samples for clinical trial support.
• Metabolite Identification: Aids in the identification and structural elucidation of drug metabolites by providing a stable-isotope reference.
• Quality Control & Assurance: Serves as a reference material in quality control laboratories to validate analytical methods and ensure batch-to-batch consistency of active pharmaceutical ingredients (APIs).
• Regulatory Submissions: Supports data packages for regulatory filings (e.g., FDA, EMA) by providing traceable and definitive analytical results.

Basic Information

Product Name	(2S)-trans-7-Chloro-2′,4,6-Trimethoxy-6′-Methylspiro(Benzofuran-2[3H],1′-[2]Cyclohexene)-3,4′-Dione-13C17 Solution
CAS No.	1325307-58-1
Molecular Formula	C2013C17H23ClO7
Molecular Weight	~ 494.9 g/mol (for 13C17 labeled form)
Synonyms	7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione-13C17; Spirobenzofuran-13C17 labeled standard; Carbon-13 labeled spiro compound; Stable Isotope Labeled Internal Standard; (2S,6'R)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-cyclohex-2-ene]-3,4'-dione-13C17; 13C17-Griseofulvin analog; Griseofulvin-13C17 derivative solution.
EINECS	Contact for details

Quality Control

Every batch of our (2S)-trans-7-Chloro-2′,4,6-Trimethoxy-6′-Methylspiro(Benzofuran-2[3H],1′-[2]Cyclohexene)-3,4′-Dione-13C17 Solution is manufactured and analyzed under strict quality systems. The product undergoes rigorous testing to ensure high chemical purity, isotopic enrichment, and solution stability, meeting the exacting standards required for analytical research. Certificates of Analysis (COA) detailing batch-specific results for identity, assay, isotopic purity, and solvent content are provided and traceable to relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. The solution is provided in a suitable organic solvent; handle with appropriate precautions in a well-ventilated area.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (by chromatographic area)
Isotopic Purity (13C)	≥ 99 atom % 13C (by MS)
Chemical Purity	≥ 98.0%
Solvent	As specified (e.g., Acetonitrile, Methanol)
Concentration	Typically 0.1 - 1.0 mg/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.