Description

2-(4-Methoxyphenyl)-4-Phenyl-1H-Imidazole-5-Thiol is a specialized heterocyclic organic compound featuring a unique imidazole-thiol core substituted with methoxyphenyl and phenyl groups. This molecular architecture makes it a valuable advanced intermediate for the synthesis of complex molecules in pharmaceutical and materials science research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly those targeting enzymes or receptors where the imidazole-thiol moiety is critical for binding.
• Agrochemical Research: Used in developing novel fungicides, herbicides, or plant growth regulators that leverage its specific heterocyclic structure.
• Material Science Precursor: Serves as a monomer or ligand in the development of specialized polymers, coordination complexes, or metal-organic frameworks (MOFs).
• Chemical Biology Probe: Utilized in research to create molecular probes for studying biological processes due to its reactive thiol group and aromatic system.
• Catalyst Ligand Synthesis: Acts as a precursor for creating novel ligands used in homogeneous catalysis for asymmetric synthesis.

Basic Information

Product Name	2-(4-Methoxyphenyl)-4-Phenyl-1H-Imidazole-5-Thiol
CAS No.	1325304-88-8
Molecular Formula	C16H14N2OS
Molecular Weight	282.36 g/mol
Synonyms	2-(4-Methoxyphenyl)-4-phenyl-1H-imidazole-5-thiol; 4-(4-Methoxyphenyl)-2-phenyl-1H-imidazole-5-thiol; 5-Mercapto-2-(4-methoxyphenyl)-4-phenylimidazole; 2-p-Methoxyphenyl-4-phenyl-5-mercaptoimidazole; 2-(4-Methoxyphenyl)-4-phenyl-5-imidazolethiol; 5-Thiol-2-(4-methoxyphenyl)-4-phenylimidazole; 1325304-88-8; 4-Phenyl-2-(4-methoxyphenyl)-1H-imidazole-5-thiol
EINECS	Contact for details

Quality Control

Our production of 2-(4-Methoxyphenyl)-4-Phenyl-1H-Imidazole-5-Thiol adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting cGMP-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.