Description

{[5-(2-Thienyl)Isoxazol-3-Yl]Methyl}Amine Hydrochloride is a high-purity, specialized organic building block featuring a fused isoxazole-thiophene heterocyclic system. This compound is of significant value in pharmaceutical research and development, serving as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization campaigns due to its unique heterocyclic scaffold.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides and herbicides, leveraging the biological activity of the isoxazole moiety.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Advanced Material Precursor: Potential starting material for the synthesis of organic semiconductors or ligands for catalytic systems, given its conjugated π-system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales, from milligram to kilogram.

Basic Information

Product Name	{[5-(2-Thienyl)Isoxazol-3-Yl]Methyl}Amine Hydrochloride
CAS No.	1323536-42-0
Molecular Formula	C8H9ClN2OS
Molecular Weight	216.68 g/mol
Synonyms	1-[(5-Thiophen-2-yl-1,2-oxazol-3-yl)methyl]amine hydrochloride; 3-(Aminomethyl)-5-(2-thienyl)isoxazole hydrochloride; (5-Thiophen-2-ylisoxazol-3-yl)methanamine hydrochloride; {[5-(2-Thienyl)-1,2-oxazol-3-yl]methyl}amine hydrochloride; Aminomethyl-5-(2-thienyl)isoxazole HCl; 1323536-42-0; 5-(Thiophen-2-yl)isoxazol-3-ylmethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our {[5-(2-Thienyl)Isoxazol-3-Yl]Methyl}Amine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.