Description

tert-Butyl (4-Methylthiazol-5-Yl)Carbamate is a high-purity, protected heterocyclic amine building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily sought after by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes, inhibitors, and tool compounds for biological research.
• Peptidomimetics & Bioisosteres: The thiazole ring and protected amine functionality make it valuable for designing peptide mimics and bioisosteric replacements.
• Material Science Research: Potential precursor for specialty polymers or functional materials requiring specific heterocyclic motifs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	tert-Butyl (4-Methylthiazol-5-Yl)Carbamate
CAS No.	1318758-14-3
Molecular Formula	C9H14N2O2S
Molecular Weight	214.28 g/mol
Synonyms	5-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-methylthiazole; 4-Methyl-5-[(tert-butoxycarbonyl)amino]thiazole; tert-Butyl N-(4-methyl-1,3-thiazol-5-yl)carbamate; Boc-4-Methyl-5-aminothiazole; 5-(Boc-amino)-4-methylthiazole; (4-Methylthiazol-5-yl)carbamic acid tert-butyl ester; N-Boc-5-amino-4-methylthiazole
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Methylthiazol-5-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.