Description

1-Boc-4-Bromo-3-Hydroxy-1H-Indole is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in the strategic protection of the indole nitrogen and the presence of orthogonal reactive sites, enabling precise and complex molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides due to its bioactive indole core.
• Organic Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group allows for selective reactions and deprotection sequences in multi-step syntheses.
• Research & Development: Critical for academic and industrial R&D labs exploring new chemical entities and reaction methodologies.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals and dyes.

Basic Information

Product Name	1-Boc-4-Bromo-3-Hydroxy-1H-Indole
CAS No.	1318104-12-9
Molecular Formula	C₁₃H₁₄BrNO₃
Molecular Weight	312.16 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-4-bromo-3-hydroxy-1H-indole; 4-Bromo-3-hydroxy-1H-indole-1-carboxylic acid tert-butyl ester; tert-Butyl 4-bromo-3-hydroxy-1H-indole-1-carboxylate; 4-Bromo-3-hydroxyindole-1-carboxylic acid tert-butyl ester; 1-Boc-4-bromo-3-hydroxyindole; Boc-4-Br-3-OH-indole; 1-(tert-Butoxycarbonyl)-4-bromo-3-hydroxyindole
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Bromo-3-Hydroxy-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.