Description

2-Bromo-4-(Trifluoromethoxy)Benzyl Alcohol is a high-value, multi-functional aromatic building block featuring both bromine and trifluoromethoxy substituents. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, ligand synthesis, and the development of novel organic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: The bromine atom provides a versatile handle for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), making it valuable for creating complex ligands for catalysis.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals, organic semiconductors, and polymers with tailored properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	2-Bromo-4-(Trifluoromethoxy)Benzyl Alcohol
CAS No.	1316273-53-6
Molecular Formula	C8H6BrF3O2
Molecular Weight	271.04 g/mol
Synonyms	[2-Bromo-4-(trifluoromethoxy)phenyl]methanol; 1-(Bromomethyl)-2-(trifluoromethoxy)benzene-4-ol (ambiguous); α-Bromo-α-(trifluoromethoxy)-p-tolyl alcohol; (2-Bromo-4-trifluoromethoxyphenyl)methanol; 2-Bromo-4-(trifluoromethoxy)benzenemethanol; 4-Trifluoromethoxy-2-bromobenzyl alcohol
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(Trifluoromethoxy)Benzyl Alcohol is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.