Description

1H-Azepine-2-Methanol, Hexahydro-, (2S)- is a high-purity chiral building block of significant interest in advanced organic synthesis. Its value lies in its functionalized azepane core, which serves as a key scaffold for constructing complex molecules with potential biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly those targeting the central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides, leveraging its structural complexity for enhanced specificity.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric catalysis to create enantiomerically enriched compounds.
• Chemical Biology Probe Development: Employed in academic and industrial research to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke intermediates for clients.

Basic Information

Product Name	1H-Azepine-2-Methanol, Hexahydro-, (2S)-
CAS No.	1314999-26-2
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	(2S)-Hexahydro-1H-azepine-2-methanol; (S)-2-(Hydroxymethyl)azepane; (S)-Azepane-2-methanol; (2S)-2-(Hydroxymethyl)hexahydro-1H-azepine; (S)-2-Hydroxymethylazepane; (S)-2-Azepanemethanol; (2S)-2-(Hydroxymethyl)perhydroazepine; L-Hexahydro-1H-azepine-2-methanol
EINECS	Contact for details

Quality Control

Our 1H-Azepine-2-Methanol, Hexahydro-, (2S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.