Description

tert-Butyl n-[(5-Formylthiophen-2-Yl)Methyl]Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a reactive formyl group on a thiophene ring, protected by a Boc (tert-butoxycarbonyl) group. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry where it serves as a versatile building block for drug discovery and development. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for small molecule therapeutics targeting various diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its reactive aldehyde functionality for further derivatization.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides, leveraging the thiophene moiety.
• Peptide Mimetics & Conjugation: The Boc-protected amine allows for its incorporation into peptide chains or its use as a linker for bioconjugation strategies.
• Material Science Research: Potential monomer or precursor for functionalized polymers and organic electronic materials containing heterocyclic units.

Basic Information

Item	Detail
Product Name	tert-Butyl n-[(5-Formylthiophen-2-Yl)Methyl]Carbamate
CAS No.	1314538-74-3
Molecular Formula	C11H15NO3S
Molecular Weight	241.31 g/mol
Synonyms	Boc-5-formyl-2-thiophenemethylamine; tert-Butyl (5-formylthiophen-2-yl)methylcarbamate; N-Boc-2-(aminomethyl)-5-thiophenecarboxaldehyde; 5-Formyl-2-thiophenemethylamine N-Boc derivative; (5-Formylthiophen-2-yl)methylcarbamic acid tert-butyl ester; 2-(((tert-Butoxycarbonyl)amino)methyl)thiophene-5-carbaldehyde; Boc-Amt(5-CHO)
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[(5-Formylthiophen-2-Yl)Methyl]Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.