Description

3-(Boc-Amino)-3-(3-Chlorophenyl)-1-Propanol is a protected amino alcohol derivative featuring a tert-butoxycarbonyl (Boc) group and a chlorophenyl moiety. This compound serves as a crucial chiral building block and advanced pharmaceutical intermediate in modern organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and other complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Peptidomimetics & PROTACs: Used in constructing complex molecular architectures for drug discovery programs targeting protein-protein interactions.
• Asymmetric Synthesis: Employed as a starting material or chiral auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in enantioselective transformations.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, structurally complex intermediates.

Basic Information

Product Name	3-(Boc-Amino)-3-(3-Chlorophenyl)-1-Propanol
CAS No.	1314406-54-6
Molecular Formula	C₁₄H₂₀ClNO₃
Molecular Weight	285.77 g/mol
Synonyms	1-Propanol, 3-[(1,1-dimethylethoxy)carbonyl]amino-3-(3-chlorophenyl)-; 3-[(tert-Butoxycarbonyl)amino]-3-(3-chlorophenyl)propan-1-ol; 3-(Boc-amino)-3-(3-chlorophenyl)propanol; (3R/S)-3-(Boc-amino)-3-(3-chlorophenyl)-1-propanol; tert-Butyl [3-(3-chlorophenyl)-3-hydroxypropyl]carbamate; Boc-3-(3-chlorophenyl)-3-aminopropanol
EINECS	Contact for details

Quality Control

Our 3-(Boc-Amino)-3-(3-Chlorophenyl)-1-Propanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.