Description

(1H-Pyrazol-3-Yl)Boronic Acid Hydrochloride is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing pyrazole-containing drug candidates in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides featuring heterocyclic scaffolds.
• Material Science: Serves as a precursor for creating functionalized polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and affinity ligands for studying biological systems.
• Catalyst & Ligand Development: Used to prepare novel boron-containing ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis services targeting complex, multi-step organic molecules.

Basic Information

Product Name	(1H-Pyrazol-3-Yl)Boronic Acid Hydrochloride
CAS No.	1314216-33-5
Molecular Formula	C3H6BClN2O2
Molecular Weight	148.36 g/mol
Synonyms	3-Pyrazolylboronic Acid Hydrochloride; 1H-Pyrazol-3-ylboronic Acid HCl; (1H-Pyrazol-3-yl)boronic Acid Hydrochloride; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Hydrochloride (protected form precursor); Pyrazole-3-boronic Acid Hydrochloride; 3-Boronopyrazole Hydrochloride
EINECS	Contact for details

Quality Control

Our (1H-Pyrazol-3-Yl)Boronic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 2.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.