Description

1,2-Benzene-13C6-Dicarboxylic Acid is a stable isotope-labeled derivative of phthalic acid, where all six carbon atoms in the benzene ring are the carbon-13 (13C) isotope. This high-purity labeled compound is essential as an internal standard for quantitative mass spectrometry, enabling precise and accurate analysis in complex matrices. It is primarily required by analytical laboratories, pharmaceutical researchers, and environmental testing facilities for method development, validation, and regulatory compliance in trace-level quantification.

Application

• Internal Standard for LC-MS/MS and GC-MS: Used for the accurate quantification of phthalic acid, phthalate esters, and related metabolites in pharmacokinetic and bioanalytical studies.
• Metabolic Pathway Tracing: Serves as a tracer in 13C-isotope labeling experiments to study metabolic fluxes and degradation pathways in biological and environmental systems.
• Environmental Analysis: Critical for monitoring and quantifying phthalate plasticizers and their breakdown products in water, soil, and consumer products with high precision.
• Pharmaceutical Impurity Profiling: Employed in the development and validation of analytical methods to identify and quantify genotoxic impurities and degradation products in active pharmaceutical ingredients (APIs).
• Food Safety Testing: Used in methods to detect migration of phthalates from packaging materials into foodstuffs, ensuring compliance with global safety regulations.
• Forensic and Doping Control: Acts as a reliable reference standard in forensic toxicology and anti-doping programs for the definitive identification of substances.

Basic Information

Product Name	1,2-Benzene-13C6-Dicarboxylic Acid
CAS No.	1313734-99-4
Molecular Formula	13C6H6O4
Molecular Weight	172.07 g/mol (for 13C6)
Synonyms	Phthalic-13C6 Acid; Benzene-1,2-dicarboxylic-13C6 Acid; 1,2-Benzenedicarboxylic-13C6 Acid; o-Phthalic-13C6 Acid; 13C6-Phthalic Acid; Isotopically Labeled Phthalic Acid; [13C6]-Phthalic Acid; CAS 1313734-99-4
EINECS	Contact for details

Quality Control

Every batch of 1,2-Benzene-13C6-Dicarboxylic Acid is produced and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment, and identification of any unlabeled species. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications for use as a certified reference material. Our quality commitment ensures reliability for your most demanding analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.