Description

3-Amino-4-Bromo-5-Methyl-Thiophene-2-Carboxylic Acid Methyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both amino and bromo substituents on a thiophene core, makes it a critical intermediate for constructing complex molecules with tailored electronic and biological properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas requiring thiophene-based scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated heterocyclic structure.
• Material Science Research: Serves as a precursor for functionalized polymers and organic electronic materials, such as organic semiconductors and conductive polymers.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Amino-4-Bromo-5-Methyl-Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	1313712-49-0
Molecular Formula	C7H8BrNO2S
Molecular Weight	250.11 g/mol
Synonyms	Methyl 3-Amino-4-Bromo-5-Methylthiophene-2-Carboxylate; 3-Amino-4-bromo-5-methyl-2-thiophenecarboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-4-bromo-5-methyl-, methyl ester; 4-Bromo-3-amino-5-methylthiophene-2-carboxylic acid methyl ester; Methyl 4-bromo-3-amino-5-methylthiophene-2-carboxylate; 1313712-49-0; 3-Amino-4-bromo-5-methylthiophene-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our production of 3-Amino-4-Bromo-5-Methyl-Thiophene-2-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.