Description

n-(2-Mercapto-1-oxopropyl)-L-serine is a specialized, high-purity amino acid derivative featuring both a mercapto (thiol) and an oxopropyl functional group. This unique bifunctional structure makes it a valuable building block for advanced pharmaceutical synthesis and biochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel peptide-based therapeutics and targeted molecular probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel peptide drugs and enzyme inhibitors.
• Bioconjugation Reagent: Used for site-specific modification of proteins, antibodies, and other biomolecules via its reactive thiol group.
• Research Chemical: Employed in academic and industrial R&D for studying enzyme mechanisms and developing new biochemical assays.
• Ligand Synthesis: Serves as a precursor for creating chelating agents and ligands in metal-catalyzed reactions or diagnostic imaging agents.
• Peptide Mimetic Development: Incorporated into peptide chains to introduce specific structural or functional properties, enhancing stability or bioactivity.

Basic Information

Product Name	n-(2-Mercapto-1-oxopropyl)-L-serine
CAS No.	1313496-17-1
Molecular Formula	C6H11NO4S
Molecular Weight	193.22 g/mol
Synonyms	L-Serine, N-(2-mercapto-1-oxopropyl)-; N-Acetyl-L-serine thioester derivative; (2S)-2-[[(2R)-2-Mercaptopropanoyl]amino]-3-hydroxypropanoic acid; 3-Hydroxy-N-[(2R)-2-mercapto-1-oxopropyl]-L-alanine; Mercaptopropionylserine; Acetylthioalanine derivative; Amino acid thioester; Research compound 1313496-17-1
EINECS	Contact for details

Quality Control

Our n-(2-Mercapto-1-oxopropyl)-L-serine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.