Description

n-(2-Mercapto-1-oxopropyl)-L-valine is a specialized amino acid derivative featuring a thiol (mercapto) functional group. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or building block for synthesizing more complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in protease inhibitor research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry to introduce specific structural motifs or functional handles.
• Bioconjugation Chemistry: The reactive thiol group enables site-specific conjugation to proteins, antibodies, or other biomolecules for drug delivery systems.
• Chemical Biology Research: Serves as a tool compound or precursor in studying enzyme mechanisms and protein-ligand interactions.
• Precursor for Chelating Agents: Can be utilized to develop ligands for metal catalysis or medical imaging agents.

Basic Information

Product Name	n-(2-Mercapto-1-oxopropyl)-L-valine
CAS No.	1313496-16-0
Molecular Formula	C8H15NO3S
Molecular Weight	205.27 g/mol
Synonyms	L-Valine, N-(2-mercapto-1-oxopropyl)-; N-(2-Mercaptopropionyl)-L-valine; 2-Mercaptopropanoyl-L-valine; (2S)-2-[(2R)-2-Mercaptopropanamido]-3-methylbutanoic acid; Mercaptopropionylvaline; Thiolated valine derivative; CAS 1313496-16-0
EINECS	Contact for details

Quality Control

Our n-(2-Mercapto-1-oxopropyl)-L-valine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.