Description

5-(Boc-Amino)-3-Chloro-1-Methyl-1H-Indazole is a high-purity, protected amino-indazole derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and pharmaceutical development, enabling the efficient construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: The Boc-protected amino group makes it valuable for constructing indazole-containing peptidomimetics and bioisosteres.
• Agrochemical Development: Intermediate in the research and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Building block for creating labeled compounds and molecular probes used in biochemical and cellular assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	5-(Boc-Amino)-3-Chloro-1-Methyl-1H-Indazole
CAS No.	1312949-21-5
Molecular Formula	C13H16ClN3O2
Molecular Weight	281.74 g/mol
Synonyms	1H-Indazole-5-amine, 3-chloro-1-methyl-, 1,1-dimethylethyl ester; tert-Butyl (3-chloro-1-methyl-1H-indazol-5-yl)carbamate; 5-((tert-Butoxycarbonyl)amino)-3-chloro-1-methyl-1H-indazole; Boc-5-amino-3-chloro-1-methylindazole; N-Boc-5-amino-3-chloro-1-methylindazole; 3-Chloro-1-methyl-1H-indazol-5-yl-carbamic acid tert-butyl ester; 1312949-21-5; 5-(tert-Butoxycarbonylamino)-3-chloro-1-methylindazole
EINECS	Contact for details

Quality Control

Our 5-(Boc-Amino)-3-Chloro-1-Methyl-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements. We are committed to supplying material that meets the high standards expected in pharmaceutical R&D and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.