Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Chloro-2-Methyl-1-(Phenylsulfonyl)-, Methyl Ester is a high-purity, synthetically advanced heterocyclic building block designed for sophisticated pharmaceutical and agrochemical research. This compound is a critical intermediate in the synthesis of complex molecules, offering a unique scaffold for medicinal chemistry and drug discovery programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in oncology, CNS, and antiviral research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its privileged pyrrolopyridine core.
• Agrochemical Development: Acts as a precursor in the creation of new pesticides and herbicides with targeted modes of action.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and methodological development.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Chloro-2-Methyl-1-(Phenylsulfonyl)-, Methyl Ester
CAS No.	1312755-55-7
Molecular Formula	C16H13ClN2O4S
Molecular Weight	364.80 g/mol
Synonyms	Methyl 5-chloro-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 5-Chloro-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-chloro-2-methyl-1-(phenylsulfonyl)-, methyl ester; 1312755-55-7; 1-(Phenylsulfonyl)-5-chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Chloro-2-Methyl-1-(Phenylsulfonyl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply under cGMP guidelines for advanced clinical stage applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.