Description

3-Chloro-6-(1-Methylethyl)-1H-Indole-2-Carboxylic Acid is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chlorinated and carboxylic acid functionalities into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used as a core structure for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of biochemical tools.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	3-Chloro-6-(1-Methylethyl)-1H-Indole-2-Carboxylic Acid
CAS No.	1312137-82-8
Molecular Formula	C₁₂H₁₂ClNO₂
Molecular Weight	237.68 g/mol
Synonyms	3-Chloro-6-isopropyl-1H-indole-2-carboxylic acid; 6-Isopropyl-3-chloroindole-2-carboxylic acid; 2-Carboxy-3-chloro-6-isopropylindole; 3-Chloro-6-(propan-2-yl)-1H-indole-2-carboxylic acid; 1312137-82-8; 3-Chloro-6-isopropylindole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-(1-Methylethyl)-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.