Description

(3R)-2,3-Dihydro-3-(2-Propyn-1-Ylamino)-1H-Inden-1-One CAS NO 1312077-05-6 is a high-purity chiral indanone derivative featuring a propargylamine side chain, serving as a critical synthetic intermediate in advanced organic chemistry. Its precise stereochemistry and functional groups make it an invaluable building block for constructing complex molecular architectures with targeted biological activity. This compound is essential for research and development teams in the pharmaceutical and agrochemical sectors focused on creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Building block for developing new generation pesticides and herbicides with enhanced specificity and lower environmental impact.
• Chemical Biology Probe Development: Used to create tool compounds for studying enzyme mechanisms and protein-ligand interactions due to its reactive alkyne handle.
• Asymmetric Catalysis Ligand Synthesis: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Material Science Research: Intermediate for specialty polymers and advanced organic electronic materials requiring specific molecular geometry.

Basic Information

Product Name	(3R)-2,3-Dihydro-3-(2-Propyn-1-Ylamino)-1H-Inden-1-One
CAS No.	1312077-05-6
Molecular Formula	C₁₂H₁₁NO
Molecular Weight	185.22 g/mol
Synonyms	(3R)-3-(Prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-1-one; (R)-3-(Prop-2-yn-1-ylamino)indan-1-one; 1H-Inden-1-one, 2,3-dihydro-3-[(2-propyn-1-yl)amino]-, (3R)-; (3R)-3-(2-Propynylamino)indan-1-one; (R)-3-(Prop-2-ynylamino)indan-1-one; (R)-3-(Prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-1-one; (3R)-3-(Prop-2-ynylamino)-2,3-dihydro-1H-inden-1-one; (R)-3-(Propargylamino)indan-1-one
EINECS	Contact for details

Quality Control

Our (3R)-2,3-Dihydro-3-(2-Propyn-1-Ylamino)-1H-Inden-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.