Description

6-Chloro-1H-Indazole-5-Carbonitrile is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive indazole core.
• Material Science: Acts as a building block for organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology: Employed as a molecular probe or scaffold in biochemical assay development and target identification.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	6-Chloro-1H-Indazole-5-Carbonitrile
CAS No.	1312008-67-5
Molecular Formula	C8H4ClN3
Molecular Weight	177.59 g/mol
Synonyms	6-Chloro-1H-indazole-5-carbonitrile; 5-Cyano-6-chloro-1H-indazole; 6-Chloro-5-cyanoindazole; 1H-Indazole-5-carbonitrile, 6-chloro-; 6-Chloro-1H-indazole-5-carbonitrile; 1312008-67-5; 6-Chloroindazole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Chloro-1H-Indazole-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH guidelines ensure material suitability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.