Description

4-[2-(Piperidin-4-Yl)-1,3-Thiazol-4-Yl]Pyridine Dihydrochloride is a high-purity, non-racemic pharmaceutical intermediate and research chemical of significant interest in modern drug discovery. This compound matters because it serves as a critical building block for synthesizing novel, biologically active molecules targeting central nervous system and other therapeutic areas. Pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers need this precisely characterized salt form to ensure reproducibility and efficacy in their development pipelines.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potent and selective receptor modulators and enzyme inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and validate novel drug targets.
• Active Pharmaceutical Ingredient (API) Development: Serves as a starting material or an advanced intermediate in the GMP-scale production of candidate drugs.
• Chemical Biology Probes: Utilized to develop probes for understanding protein-ligand interactions and cellular signaling mechanisms.

Basic Information

Product Name	4-[2-(Piperidin-4-Yl)-1,3-Thiazol-4-Yl]Pyridine Dihydrochloride
CAS No.	1311315-01-1
Molecular Formula	C13H16N3S • 2HCl
Molecular Weight	323.27 g/mol (Free base: 246.35 g/mol)
Synonyms	4-[2-(4-Piperidinyl)-4-thiazolyl]pyridine dihydrochloride; 4-(2-(Piperidin-4-yl)thiazol-4-yl)pyridine dihydrochloride; 4-(2-(Piperidin-4-yl)-1,3-thiazol-4-yl)pyridine hydrochloride (1:2); UNII-6V8R8J8Q4F; 1311315-01-1; 4-(2-(4-Piperidyl)-1,3-thiazol-4-yl)pyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-[2-(Piperidin-4-Yl)-1,3-Thiazol-4-Yl]Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.