Description

Boc-3-Aminopyridine-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry, particularly in cross-coupling reactions. This compound is a critical building block for the efficient and selective construction of complex molecules in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences industry for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediates: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides through efficient carbon-carbon bond formation.
• Material Science Research: Serves as a building block for creating functionalized organic frameworks, polymers, and advanced electronic materials.
• Chemical Biology Probes: Enables the synthesis of tagged molecules for studying biological pathways and target engagement.
• Process Chemistry & Scale-up: Provides a stable, protected boronate ester for reliable and scalable manufacturing processes in GMP and non-GMP environments.
• Academic & Contract Research: A valuable reagent for methodology development and library synthesis in academic laboratories and CROs (Contract Research Organizations).

Basic Information

Item	Detail
Product Name	Boc-3-Aminopyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310405-05-0
Molecular Formula	C16H25BN2O4
Molecular Weight	320.20 g/mol
Synonyms	tert-Butyl (2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)carbamate; 3-((tert-Butoxycarbonyl)amino)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Boc-3-Amino-2-pyridylboronic acid pinacol ester; N-Boc-3-amino-2-pyridineboronic acid pinacol ester; 2-Borono-3-((tert-butoxycarbonyl)amino)pyridine pinacol ester
EINECS	Contact for details

Quality Control

Our Boc-3-Aminopyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.