Description

5-tert-Butyloxycarbonylamino-2-Chloropyridine-3-Boronic Acid Pinacol Ester is a high-value, multi-functional boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical protected intermediate, enabling the controlled introduction of the 3-boronic acid functionality into complex molecular architectures. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, particularly in cross-coupling reactions to construct biaryl and heterobiaryl systems.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used to create novel heterocyclic compounds for crop protection and pesticide development.
• Material Science: Serves as a precursor for functionalized organic materials and ligands for catalysis.
• Chemical Biology: Employed in the development of molecular probes and bio-conjugation tools due to its protected amine and boronic ester groups.
• Academic & Contract Research: Essential for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	5-tert-Butyloxycarbonylamino-2-Chloropyridine-3-Boronic Acid Pinacol Ester
CAS No.	1310404-53-5
Molecular Formula	C16H24BClN2O4
Molecular Weight	354.64 g/mol
Synonyms	5-((tert-Butoxycarbonyl)amino)-2-chloropyridine-3-boronic acid pinacol ester; 2-Chloro-5-[(tert-butoxycarbonyl)amino]pyridine-3-boronic acid pinacol ester; Boc-Protected 2-Chloro-5-aminopyridine-3-boronic acid pinacol ester; 2-Chloro-5-Boc-aminopyridine-3-boronic acid pinacol ester; (5-((tert-Butoxycarbonyl)amino)-2-chloropyridin-3-yl)boronic acid pinacol ester; CAS 1310404-53-5
EINECS	Contact for details

Quality Control

Our 5-tert-Butyloxycarbonylamino-2-Chloropyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.