Description

2-tert-Butyloxycarbonylamino-5-Methylpyridine-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative crucial for modern synthetic chemistry. This compound serves as a key advanced pharmaceutical intermediate (API) and building block in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical building block for forming carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a precursor in creating novel compounds for crop protection and pesticide development.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for catalysts, and functional polymers.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-tert-Butyloxycarbonylamino-5-Methylpyridine-3-Boronic Acid Pinacol Ester
CAS No.	1310404-52-4
Molecular Formula	C₁₇H₂₇BN₂O₄
Molecular Weight	334.22 g/mol
Synonyms	5-Methyl-2-((tert-butoxycarbonyl)amino)pyridine-3-boronic acid pinacol ester; 2-(Boc-amino)-5-methylpyridine-3-boronic acid pinacol ester; 2-(N-Boc-amino)-5-methyl-3-pyridineboronic acid pinacol ester; 2-((tert-Butoxycarbonyl)amino)-5-methylpyridine-3-boronic acid pinacol ester; 3-Borono-5-methyl-2-((tert-butoxycarbonyl)amino)pyridine pinacol ester; Boc-5-Methyl-2-aminopyridine-3-boronic acid pinacol ester; 1310404-52-4; 2-(tert-Butoxycarbonylamino)-5-methylpyridin-3-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-tert-Butyloxycarbonylamino-5-Methylpyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (¹H and ¹³C), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full specification data are provided for every shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.