Description

6-(3-Methylpiperidin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters because it serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex heterocyclic structures.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Probe Development: Utilized to create tagged molecules and bioconjugates for studying biological pathways and target engagement.
• Catalyst Ligand Preparation: Serves as a precursor for synthesizing sophisticated ligand systems used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	6-(3-Methylpiperidin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310404-13-7
Molecular Formula	C17H27BN2O2
Molecular Weight	302.22 g/mol
Synonyms	6-(3-Methyl-1-piperidinyl)-2-pyridineboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(3-methylpiperidin-1-yl)pyridine; 6-(3-Methylpiperidin-1-yl)pyridine-2-boronic acid pinacol ester; 1-[6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]-3-methylpiperidine; Boronic acid, B-[6-(3-methyl-1-piperidinyl)-2-pyridinyl]-, 1,1-dimethylethyl ester; 1310404-13-7; 6-(3-Methylpiperidino)pyridine-2-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-(3-Methylpiperidin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.