Description

5-Fluoro-6-Benzoxypyridine-3-Boronic Acid is a high-value boronic acid derivative, a key building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing the benzoxypyridine scaffold.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid reagent for palladium-catalyzed carbon-carbon bond formation, a cornerstone of medicinal chemistry.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of molecular probes and inhibitors.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and library synthesis in academic and CRO laboratories.

Basic Information

Product Name	5-Fluoro-6-Benzoxypyridine-3-Boronic Acid
CAS No.	1310384-31-6
Molecular Formula	C12H9BFNO3
Molecular Weight	245.02 g/mol
Synonyms	(5-Fluoro-6-benzoxypyridin-3-yl)boronic acid; 3-Borono-5-fluoro-6-benzoxypyridine; 5-Fluoro-6-benzoxypyridine-3-boronic acid pinacol ester; 5-Fluoro-6-(benzyloxy)pyridine-3-boronic acid (common misnomer); 5-Fluoro-6-benzoxypyridin-3-ylboronic acid; 1310384-31-6; Boronic acid, B-(5-fluoro-6-benzoxypyridin-3-yl)-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Benzoxypyridine-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.