Description

2-Chloro-5-Fluoro-1-Methyl-1H-Indole-3-Carbaldehyde is a high-value, multi-functional indole derivative serving as a critical synthetic intermediate. Its molecular structure, featuring halogen substituents and an aldehyde group, makes it an essential building block for constructing complex heterocyclic compounds. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, anti-cancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that require complex indole-based scaffolds.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Organic Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as a substrate for constructing fused heterocyclic systems via its reactive aldehyde group.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-Chloro-5-Fluoro-1-Methyl-1H-Indole-3-Carbaldehyde
CAS No.	1310141-83-3
Molecular Formula	C10H7ClFNO
Molecular Weight	211.62 g/mol
Synonyms	2-Chloro-5-fluoro-1-methylindole-3-carboxaldehyde; 1-Methyl-2-chloro-5-fluoroindole-3-carbaldehyde; 3-Formyl-2-chloro-5-fluoro-1-methylindole; 2-Chloro-5-fluoro-1-methyl-1H-indole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 2-chloro-5-fluoro-1-methyl-; CAS 1310141-83-3
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-1-Methyl-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.