Description

2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-value, functionalized aniline derivative featuring a pinacol boronate ester group. This compound is a critical pharmaceutical intermediate and Suzuki-Miyaura cross-coupling building block, enabling the efficient construction of complex biaryl structures. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronate ester group facilitates palladium-catalyzed coupling with aryl/heteroaryl halides, a cornerstone reaction in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific halogenated aniline backbones.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Organic Electronic Materials: A potential monomer or intermediate in the synthesis of conjugated polymers and small molecules for OLEDs and organic semiconductors.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries for high-throughput screening.

Basic Information

Product Name	2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1309982-17-9
Molecular Formula	C12H17BClNO2
Molecular Weight	253.53 g/mol
Synonyms	2-Amino-3-chlorophenylboronic acid pinacol ester; (2-Amino-3-chlorophenyl)boronic acid pinacol ester; 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; 3-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 2-Chloro-6-(pinacolatoboryl)aniline; 2-Chloro-6-(pinacolboron)aniline; 2-Chloro-6-(pinacolboronate)aniline; 2-Chloro-6-(pinacolboranyl)aniline
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.