Description

5-Phenyl-3,4-Dihydroisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the isoquinolinone class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers targeting the development of new therapeutic agents, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates with potential biological activity.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex polycyclic frameworks and heterocyclic systems due to its reactive functional groups.
• Biochemical Research: Potential use in developing enzyme inhibitors or receptor ligands for biochemical assays and pharmacological studies.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals and high-value agrochemical intermediates.
• Academic Research: A valuable compound for methodological development in organic synthesis and heterocyclic chemistry at universities and research institutes.

Basic Information

Item	Detail
Product Name	5-Phenyl-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	1309955-15-4
Molecular Formula	C₁₅H₁₃NO
Molecular Weight	223.27 g/mol
Synonyms	5-Phenyl-1,2,3,4-tetrahydroisoquinolin-1-one; 5-Phenyl-3,4-dihydro-1(2H)-isoquinolinone; 5-Phenyl-1,2,3,4-tetrahydroisoquinoline-1-one; 1309955-15-4; 5-Phenyl-3,4-dihydroisoquinolin-1(2H)-one; 5-Phenyldihydroisoquinolinone; 5-Phenyl-1-oxo-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 5-Phenyl-3,4-Dihydroisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.