Description

1,1'-[(1,1-Dimethylethyl)[[(1R,2E)-1-Ethyl-3-Iodo-2-Propen-1-Yl]Oxy]Silylene]Bis-Benzene is a sophisticated organosilicon compound featuring a chiral center and an iodoalkene functional group, making it a valuable intermediate for advanced chemical synthesis. Its molecular architecture is engineered to serve as a key building block in the development of novel materials and active pharmaceutical ingredients (APIs). This high-purity specialty chemical is essential for research institutions and industrial manufacturers engaged in organometallic chemistry, asymmetric synthesis, and the creation of functionalized polymers.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of complex drug candidates, particularly in oncology and neurology research.
• Advanced Material Science: Used as a functional monomer or cross-linking agent in the development of specialty silicones, liquid crystals, and high-performance polymers with tailored properties.
• Catalyst Ligand Precursor: The iodine and alkene functionalities make it a valuable precursor for constructing novel ligands used in transition metal catalysis for asymmetric transformations.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Heck, Sonogashira) to introduce complex silicon-containing motifs into target molecules.
• Agrochemical Research: Acts as an intermediate in the synthesis of novel, high-efficacy crop protection agents with specific stereochemical requirements.
• Academic & R&D: A valuable reagent for methodological studies in synthetic organic and organometallic chemistry at universities and corporate R&D centers.

Basic Information

Product Name	1,1'-[(1,1-Dimethylethyl)[[(1R,2E)-1-Ethyl-3-Iodo-2-Propen-1-Yl]Oxy]Silylene]Bis-Benzene
CAS No.	1309610-39-6
Molecular Formula	C23H29IOSi
Molecular Weight	476.47 g/mol
Synonyms	(R,E)-1-((tert-Butoxy)(diphenyl)silyl)-1-ethyl-3-iodoprop-1-ene; tert-Butyl((1R,2E)-1-ethyl-3-iodoallyloxy)diphenylsilane; (1R,2E)-1-((tert-Butoxy(diphenyl)silyl)oxy)-1-ethyl-3-iodoprop-1-ene; Diphenyl(tert-butoxy)[(1R,2E)-1-ethyl-3-iodo-2-propen-1-yl]silane; Silane, tert-butyl[(1R,2E)-1-ethyl-3-iodo-2-propen-1-yl]oxydiphenyl-; Chiral iodoalkene silyl ether; (R,E)-Iodoalkene tert-butyldiphenylsilyl (TBDPS) ether
EINECS	Contact for details

Quality Control

Every batch of 1,1'-[(1,1-Dimethylethyl)[[(1R,2E)-1-Ethyl-3-Iodo-2-Propen-1-Yl]Oxy]Silylene]Bis-Benzene is manufactured and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity, meeting the exacting standards required for pharmaceutical and advanced material applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.