Description

tert-Butyl 3-Iodo-4-Methoxy-1H-Indole-1-Carboxylate is a high-purity, synthetically valuable indole derivative, serving as a crucial protected intermediate in advanced organic synthesis. Its core value lies in enabling the precise construction of complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where the indole scaffold is a key structural motif.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting neurological disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that utilize functionalized indole structures.
• Material Science Precursor: Serves as a monomer or intermediate in the synthesis of advanced organic electronic materials and dyes.
• Academic & R&D: A versatile reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocyclic chemistry.
• Peptidomimetics & Bioconjugation: The protected carboxylate and halogenated indole core are useful for creating peptide analogs and bioconjugation linkers.

Basic Information

Product Name	tert-Butyl 3-Iodo-4-Methoxy-1H-Indole-1-Carboxylate
CAS No.	1309365-09-0
Molecular Formula	C14H16INO3
Molecular Weight	373.19 g/mol
Synonyms	1-Boc-3-iodo-4-methoxyindole; tert-Butyl 3-iodo-4-methoxy-1H-indole-1-carboxylate; 3-Iodo-4-methoxy-1H-indole-1-carboxylic acid tert-butyl ester; 1H-Indole-1-carboxylic acid, 3-iodo-4-methoxy-, 1,1-dimethylethyl ester; Boc-3-I-4-MeO-indole; 4-Methoxy-3-iodo-1H-indole-1-carboxylic acid tert-butyl ester; 1309365-09-0
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Iodo-4-Methoxy-1H-Indole-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials. For long-term storage, consider storage at -20°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.