Description

Ethyl 3-Amino-5-Bromo-1-Benzothiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its benzothiophene core structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and the production of Active Pharmaceutical Ingredients (APIs) for clinical trials.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and the exploration of new synthetic methodologies.

Basic Information

Product Name	Ethyl 3-Amino-5-Bromo-1-Benzothiophene-2-Carboxylate
CAS No.	1308649-79-7
Molecular Formula	C11H10BrNO2S
Molecular Weight	300.17 g/mol
Synonyms	Ethyl 3-Amino-5-Bromobenzo[b]thiophene-2-carboxylate; 5-Bromo-3-aminobenzo[b]thiophene-2-carboxylic Acid Ethyl Ester; 3-Amino-5-bromobenzo[b]thiophene-2-carboxylic acid ethyl ester; 2-Carbethoxy-3-amino-5-bromobenzo[b]thiophene; 1308649-79-7; Ethyl 3-amino-5-bromobenzo[b]thiophene-2-carboxylate; Ethyl 5-bromo-3-aminobenzo[b]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Amino-5-Bromo-1-Benzothiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.