Description

5-(2-Adamantyl)-1H-Indole-2-Carboxylic Acid CAS NO 1306739-17-2 is a high-purity, functionalized indole derivative featuring an adamantyl substituent, which imparts unique steric and lipophilic properties. This compound is a critical advanced pharmaceutical intermediate (API intermediate) valued for its role in the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical R&D departments focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, antiviral agents, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its rigid adamantane scaffold and modifiable carboxylic acid group.
• Organic Synthesis: Acts as a precursor for amide coupling reactions, esterification, and other derivatizations to create libraries of novel chemical entities for screening.
• Bioconjugation & Probe Development: The carboxylic acid functionality allows for conjugation to biomolecules, peptides, or fluorescent tags for biochemical and diagnostic applications.
• Material Science Research: Investigated for the development of specialty polymers or organic electronic materials where the adamantyl group can enhance thermal stability and solubility.

Basic Information

Product Name	5-(2-Adamantyl)-1H-Indole-2-Carboxylic Acid
CAS No.	1306739-17-2
Molecular Formula	C19H21NO2
Molecular Weight	295.38 g/mol
Synonyms	5-(2-Adamantyl)indole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 5-(2-adamantyl)-; 5-(Tricyclo[3.3.1.1³,⁷]dec-2-yl)-1H-indole-2-carboxylic acid; 5-(2-Adamantyl)-1H-indol-2-carboxylic acid; Adamantyl-indole-carboxylic acid; 1306739-17-2; 5-(2-Ada)ICA
EINECS	Contact for details

Quality Control

Our production of 5-(2-Adamantyl)-1H-Indole-2-Carboxylic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.