Description

2-Aminomethyl-Thiazole-4-Carboxylic Acid Ethyl Ester Dihydrochloride is a high-purity, pharmaceutically relevant chemical building block, essential for the synthesis of complex heterocyclic compounds. Its value lies in its role as a key intermediate for developing novel active pharmaceutical ingredients (APIs) and fine chemicals, offering researchers and manufacturers a reliable and well-characterized starting material. This compound is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries focused on innovation in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole core.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker for designing chemical probes and enzyme inhibitors.
• Material Science: Investigated as a monomer or additive for creating novel polymers with specific electronic or optical properties.
• Academic & Contract Research: Employed in university and CRO settings for methodological development and exploratory synthetic chemistry.

Basic Information

Product Name	2-Aminomethyl-Thiazole-4-Carboxylic Acid Ethyl Ester Dihydrochloride
CAS No.	1306603-28-0
Molecular Formula	C8H13N2O2S · 2HCl
Molecular Weight	281.18 g/mol (as free base: 201.26 g/mol)
Synonyms	Ethyl 2-(aminomethyl)thiazole-4-carboxylate dihydrochloride; 4-Thiazolecarboxylic acid, 2-(aminomethyl)-, ethyl ester, dihydrochloride; 2-(Aminomethyl)-4-thiazolecarboxylic acid ethyl ester dihydrochloride; 2-Aminomethyl-4-carbethoxythiazole dihydrochloride; AMTCE dihydrochloride; ATCE dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Aminomethyl-Thiazole-4-Carboxylic Acid Ethyl Ester Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.