Description

5-tert-Butyl-3-(1H-Pyrrol-1-Yl)-Thiophene-2-Carboxylic Acid CAS NO 1305711-48-1 is a high-purity heterocyclic carboxylic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique molecular architecture, featuring a thiophene core substituted with a tert-butyl group and a pyrrole moiety, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for creating complex heterocyclic libraries for high-throughput screening (HTS) in drug discovery.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	5-tert-Butyl-3-(1H-Pyrrol-1-Yl)-Thiophene-2-Carboxylic Acid
CAS No.	1305711-48-1
Molecular Formula	C13H15NO2S
Molecular Weight	249.33 g/mol
Synonyms	5-tert-Butyl-3-(1H-pyrrol-1-yl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-(1,1-dimethylethyl)-3-(1H-pyrrol-1-yl)-; 5-(tert-Butyl)-3-(pyrrol-1-yl)thiophene-2-carboxylic acid; 3-(1H-Pyrrol-1-yl)-5-tert-butylthiophene-2-carboxylic acid; 5-tert-Butyl-3-(1H-pyrrol-1-yl)-2-thiophenecarboxylic acid; 1305711-48-1; 5-tert-Butyl-3-pyrrol-1-yl-thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl-3-(1H-Pyrrol-1-Yl)-Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.