Description

n-Boc-3-Bromo-4-Methylindole is a high-purity, protected indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists for the synthesis of novel drug candidates, agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of indole-based active pharmaceutical ingredients (APIs) and drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel chemical space.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and pesticides.
• Material Science: Potential precursor for the development of organic electronic materials and functional dyes.
• Academic & Contract Research: Essential reagent for synthetic methodology development and custom synthesis projects in university and CRO laboratories.
• Peptidomimetics: Used in the design and synthesis of peptide analogs and mimetics for biological studies.

Basic Information

Product Name	n-Boc-3-Bromo-4-Methylindole
CAS No.	1305320-64-2
Molecular Formula	C₁₄H₁₆BrNO₂
Molecular Weight	310.19 g/mol
Synonyms	1-Boc-3-Bromo-4-Methylindole; tert-Butyl 3-Bromo-4-Methyl-1H-indole-1-carboxylate; 3-Bromo-4-Methyl-1H-indole-1-carboxylic acid tert-butyl ester; 3-Bromo-4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]indole; Boc-3-Br-4-Me-indole; 3-Bromo-4-methyl-N-Boc-indole; 1-(tert-Butoxycarbonyl)-3-bromo-4-methylindole
EINECS	Contact for details

Quality Control

Our n-Boc-3-Bromo-4-Methylindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and traceability, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.