Description

1-Boc-7-Fluoro-1H-Indazole is a high-purity, protected indazole derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the creation of novel pharmaceutical candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile, protected nitrogen heterocycle.
• Peptidomimetic Synthesis: Serves as a scaffold for designing and synthesizing peptide analogs and enzyme inhibitors.
• Agrochemical Development: Employed in the research of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	1-Boc-7-Fluoro-1H-Indazole
CAS No.	1305320-59-5
Molecular Formula	C₁₂H₁₃FN₂O₂
Molecular Weight	236.24 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-7-fluoro-1H-indazole; 7-Fluoro-1H-indazole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 7-fluoro-1H-indazole-1-carboxylate; 1-Boc-7-fluoroindazole; Boc-7-fluoroindazole; 7-Fluoro-1-Boc-indazole; 1-(tert-Butoxycarbonyl)-7-fluoro-1H-indazole; 1305320-59-5
EINECS	Contact for details

Quality Control

Our 1-Boc-7-Fluoro-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply material manufactured under cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.