Description

1-Oxo-1,8A-Dihydroisoquinoline-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing fused isoquinoline derivatives and other nitrogen-containing heterocycles of research interest.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial laboratories for method development and structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules during API development.

Basic Information

Product Name	1-Oxo-1,8A-Dihydroisoquinoline-6-Carboxylic Acid
CAS No.	1301214-60-7
Molecular Formula	C11H7NO3
Molecular Weight	201.18 g/mol
Synonyms	1,8A-Dihydroisoquinoline-1-one-6-carboxylic acid; 6-Carboxy-1,8a-dihydroisoquinolin-1-one; 1-Oxo-1,8a-dihydro-6-isoquinolinecarboxylic acid; Isoquinoline-6-carboxylic acid, 1,8a-dihydro-1-oxo-; 1,8A-Dihydro-1-oxoisoquinoline-6-carboxylic Acid; CAS 1301214-60-7
EINECS	Contact for details

Quality Control

Our production of 1-Oxo-1,8A-Dihydroisoquinoline-6-Carboxylic Acid adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.