Description

5-Bromo-3-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo-[2,3-B]Pyridine-2-Carboxylic Acid is a high-value, multi-halogenated heterocyclic building block designed for advanced pharmaceutical and agrochemical research. This compound is critical for medicinal chemists seeking to introduce specific steric and electronic properties into complex molecular architectures. It is primarily utilized in the synthesis of novel active pharmaceutical ingredients (APIs) and as a key intermediate in the development of crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials and functional dyes due to its extended conjugated system.
• Chemical Biology: Employed in the design of molecular probes and enzyme inhibitors for biochemical studies.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Library Synthesis: Used in high-throughput and combinatorial chemistry for generating diverse compound libraries for screening.

Basic Information

Product Name	5-Bromo-3-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo-[2,3-B]Pyridine-2-Carboxylic Acid
CAS No.	1299607-75-2
Molecular Formula	C₁₈H₁₀BrIN₂O₄S
Molecular Weight	572.15 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-bromo-3-iodo-1-(phenylsulfonyl)-; 5-Bromo-3-iodo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 1299607-75-2; 5-Br-3-I-1-Ps-1H-Pyrrolo[2,3-b]Pyridine-2-COOH; 1-(Phenylsulfonyl)-5-bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo-[2,3-B]Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.