Description

1H-Indole-1-Ethanol, 5-Amino-2-[1,1-Dimethyl-2-(Phenylmethoxy)Ethyl]-6-Fluoro-α-[(Phenylmethoxy)Methyl]-, (αr)- is a sophisticated, high-purity indole derivative designed for advanced pharmaceutical research and development. This compound matters as a critical building block (API intermediate) in the synthesis of novel therapeutic agents, offering researchers a reliable and well-characterized starting material. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new bioactive molecules.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the efficient, scalable synthesis of complex drug molecules.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies, given its complex indole-based structure.
• Custom Synthesis: A starting point for the contract manufacturing of specialized, non-commercial chemical entities for client-specific research programs.

Basic Information

Product Name	1H-Indole-1-Ethanol, 5-Amino-2-[1,1-Dimethyl-2-(Phenylmethoxy)Ethyl]-6-Fluoro-α-[(Phenylmethoxy)Methyl]-, (αr)-
CAS No.	1294504-67-8
Molecular Formula	C29H33FN2O3
Molecular Weight	476.59 g/mol
Synonyms	5-Amino-2-[1,1-dimethyl-2-(phenylmethoxy)ethyl]-6-fluoro-α-[(phenylmethoxy)methyl]-1H-indole-1-ethanol; (αR)-5-Amino-2-[1,1-dimethyl-2-(benzyloxy)ethyl]-6-fluoro-α-[(benzyloxy)methyl]-1H-indole-1-ethanol; UNII-8Q6K5P8V3I; 8Q6K5P8V3I; (R)-5-Amino-α-(benzyloxymethyl)-2-[1,1-dimethyl-2-(benzyloxy)ethyl]-6-fluoro-1H-indole-1-ethanol; CAS 1294504-67-8
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Ethanol derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding pharmaceutical R&D. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) with full analytical data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.