Description

n-{[6-(Benzyloxy)-1H-Indol-1-Yl]Acetyl}-L-Alanine is a sophisticated, high-purity synthetic organic compound designed for advanced research and development. This molecule serves as a critical building block or intermediate in the synthesis of novel pharmaceutical candidates, particularly those targeting specific biological pathways. It is essential for medicinal chemistry programs, process development, and the creation of proprietary chemical libraries within the life sciences sector.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of new chemical entities (NCEs) for drug discovery, especially in oncology and CNS research.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point for structure-activity relationship (SAR) studies.
• Bioconjugation & Probe Development: The L-Alanine moiety and indole structure make it suitable for creating labeled probes or protein conjugates for biochemical assays.
• Process Chemistry & Scale-up: Serves as a defined intermediate for optimizing synthetic routes and scaling up production of target active pharmaceutical ingredients (APIs).
• Chemical Biology: Utilized in the development of enzyme inhibitors or receptor modulators due to its specific heterocyclic architecture.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring high-fidelity intermediates.

Basic Information

Item	Details
Product Name	n-{[6-(Benzyloxy)-1H-Indol-1-Yl]Acetyl}-L-Alanine
CAS No.	1291780-52-3
Molecular Formula	C21H20N2O4
Molecular Weight	364.40 g/mol
Synonyms	N-[(6-Benzyloxy-1H-indol-1-yl)acetyl]-L-alanine; L-Alanine, N-[(6-(phenylmethoxy)-1H-indol-1-yl)acetyl]-; (2S)-2-[[[6-(Phenylmethoxy)-1H-indol-1-yl]acetyl]amino]propanoic acid; 1291780-52-3; Benzyloxy Indole Acetyl Alanine derivative; BIA Intermediate
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and purity for research applications. Our standard grade for this intermediate typically meets a purity specification of ≥95% (by HPLC), with comprehensive identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We can support development projects requiring compliance with ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.