Description

2-Azaspiro[3.3]Heptane-2,6-Dicarboxylic Acid, 2-(Phenylmethyl) Ester is a high-value, synthetically versatile spirocyclic building block crucial for advanced organic synthesis. This compound is engineered to serve as a key intermediate in the development of complex pharmacologically active molecules, offering a rigid, three-dimensional scaffold that is highly sought after in modern drug discovery. It is primarily targeted at research and development teams within the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate with novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its unique spirocyclic structure for enhanced biological activity and selectivity.
• Ligand and Catalyst Development: Employed in the creation of sophisticated chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science: Acts as a monomer or cross-linking agent in the research of advanced polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized to construct molecular probes for studying enzyme function and protein-protein interactions within biological systems.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, multifunctional heterocyclic frameworks.

Basic Information

Product Name	2-Azaspiro[3.3]Heptane-2,6-Dicarboxylic Acid, 2-(Phenylmethyl) Ester
CAS No.	1291487-33-6
Molecular Formula	C16H17NO4
Molecular Weight	287.31 g/mol
Synonyms	2-(Benzyloxycarbonyl)-2-azaspiro[3.3]heptane-6-carboxylic acid; 2-[(Phenylmethoxy)carbonyl]-2-azaspiro[3.3]heptane-6-carboxylic acid; 2-Cbz-2-azaspiro[3.3]heptane-6-carboxylic acid; 2-Azaspiro[3.3]heptane-2,6-dicarboxylic acid 2-benzyl ester; 2-Benzyl 2-azaspiro[3.3]heptane-2,6-dicarboxylate; 6-Carboxy-2-azaspiro[3.3]heptane-2-carboxylic acid benzyl ester; Z-Protected 2-azaspiro[3.3]heptane-6-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Azaspiro[3.3]Heptane-2,6-Dicarboxylic Acid, 2-(Phenylmethyl) Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.