Description

(2-Bromo-5-Thiazolyl)-4-Morpholinylmethanone is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific thiazole and morpholine pharmacophores into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the thiazole moiety imparts specific biological activity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science Research: Employed in the synthesis of novel organic electronic materials and ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Industrial R&D: Used in discovery chemistry programs for hit-to-lead and lead optimization processes.

Basic Information

Product Name	(2-Bromo-5-Thiazolyl)-4-Morpholinylmethanone
CAS No.	1290136-88-7
Molecular Formula	C8H9BrN2O2S
Molecular Weight	277.14 g/mol
Synonyms	2-Bromo-5-morpholin-4-ylcarbonyl-1,3-thiazole; 4-[(2-Bromo-1,3-thiazol-5-yl)carbonyl]morpholine; Morpholine, 4-[(2-bromo-5-thiazolyl)carbonyl]-; (2-Bromo-1,3-thiazol-5-yl)(morpholino)methanone; 2-Bromo-5-(morpholine-4-carbonyl)thiazole; 5-(Morpholine-4-carbonyl)thiazol-2-yl bromide
EINECS	Contact for details

Quality Control

Our (2-Bromo-5-Thiazolyl)-4-Morpholinylmethanone is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.