Description

3-Methyl-5-Nitro-7-Azaindole is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant interest in modern organic synthesis. Its value lies in its unique azaindole scaffold, which serves as a privileged structure for developing novel bioactive molecules, particularly in medicinal chemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile azaindole core.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex heterocyclic systems.
• Chemical Biology: Utilized as a molecular probe or scaffold for studying protein-ligand interactions and biological pathways.
• Material Science Research: Investigated as a precursor for organic electronic materials and photoactive compounds.

Basic Information

Item	Details
Product Name	3-Methyl-5-Nitro-7-Azaindole
CAS No.	1288998-66-2
Molecular Formula	C8H7N3O2
Molecular Weight	177.16 g/mol
Synonyms	5-Nitro-3-methyl-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 3-methyl-5-nitro-; 3-Methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 3-methyl-5-nitro-; 5-Nitro-3-methyl-1H-pyrrolo[2,3-b]pyridine; 3-Methyl-5-nitropyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-Nitro-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.