Description

Zolazepam-D3 CAS NO 1286480-83-8 is a deuterated analog of the sedative-hypnotic agent Zolazepam, specifically designed for use as an internal standard in advanced analytical chemistry. This high-purity, isotopically labeled compound is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in complex matrices. It is an essential tool for pharmaceutical research, forensic toxicology, and clinical laboratories requiring precise measurement of Zolazepam and related compounds.

Application

• Internal Standard for LC-MS/MS and GC-MS: Primary application for the quantification of Zolazepam in pharmacokinetic, bioequivalence, and forensic studies.
• Pharmaceutical R&D: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the parent drug and metabolites.
• Forensic and Clinical Toxicology: Enables accurate screening and confirmation of Zolazepam in biological samples (e.g., blood, urine, hair).
• Veterinary Medicine Research: Supports analytical methods for studying sedative agents used in animal anesthesia.
• Method Development and Validation: Serves as a critical reference material for developing robust, compliant analytical protocols.
• Quality Control in Reference Material Production: Used to certify and calibrate other analytical standards and controls.

Basic Information

Product Name	Zolazepam-D3
CAS No.	1286480-83-8
Molecular Formula	C20H14D3FN4O
Molecular Weight	339.37 g/mol
Synonyms	4-(2-Fluorophenyl)-6,8-dihydro-1-methyl-6-(trideuteriomethyl)-1H,4H,9H-imidazo[1,5-a][1,4]diazepino[5,6,1-hi]indol-9-one; Zolazepam-d3; Zolazepam (methyl-d3); Flupyrazapon-d3; CL 716-d3; CI 716-d3; Deuterated Zolazepam
EINECS	Contact for details

Quality Control

Every batch of Zolazepam-D3 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment, and solvent content to ensure compliance with your method validation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.