Description

(R)-tert-Butyl 1-(3-Fluorobenzoyl)Pyrrolidin-3-Ylcarbamate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology targets.
• API Synthesis: Used in the multi-step synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs) requiring a (R)-configured pyrrolidine scaffold.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new asymmetric catalytic processes.
• Agrochemical Development: Intermediate for creating chiral active ingredients in crop protection products.
• Chemical Biology & Proteomics: Building block for designing molecular probes and enzyme inhibitors used in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(R)-tert-Butyl 1-(3-Fluorobenzoyl)Pyrrolidin-3-Ylcarbamate
CAS No.	1286208-20-5
Molecular Formula	C16H21FN2O3
Molecular Weight	308.35 g/mol
Synonyms	Carbamic acid, N-[(3R)-1-(3-fluorobenzoyl)-3-pyrrolidinyl]-, 1,1-dimethylethyl ester; (R)-tert-Butyl (1-(3-fluorobenzoyl)pyrrolidin-3-yl)carbamate; (3R)-1-(3-Fluorobenzoyl)-N-(tert-butoxycarbonyl)pyrrolidin-3-amine; (R)-N-Boc-1-(3-fluorobenzoyl)pyrrolidin-3-amine; (R)-1-(3-Fluorobenzoyl)pyrrolidin-3-yl tert-butylcarbamate; tert-Butyl (R)-1-(3-fluorobenzoyl)pyrrolidin-3-ylcarbamate
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 1-(3-Fluorobenzoyl)Pyrrolidin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.