Description

Diisopromine-D14 is a deuterium-labeled isotopologue of the pharmaceutical compound Diisopromine, specifically designed for advanced analytical and research applications. This high-purity labeled standard is essential for ensuring accuracy and reliability in quantitative mass spectrometry and metabolic studies. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, contract research organization (CRO), and academic sectors who require precise internal standards for method development and validation.

Application

• Used as an internal standard for the accurate quantification of Diisopromine in biological matrices via LC-MS/MS and GC-MS.
• Critical in pharmacokinetic and metabolism studies to track the absorption, distribution, metabolism, and excretion (ADME) of the parent drug.
• Facilitates method development and validation in analytical laboratories to meet regulatory compliance (e.g., FDA, EMA).
• Enables drug impurity profiling and stability testing under Good Laboratory Practice (GLP) conditions.
• Supports academic and industrial research into the mechanism of action and biochemical pathways of spasmolytic agents.

Basic Information

Product Name	Diisopromine-D14
CAS No.	1286140-53-1
Molecular Formula	C23H25D14NO3 • HCl
Molecular Weight	~428.1 g/mol (deuterated form)
Synonyms	Diisopromine-d14; Deuterated Diisopromine; Diisopromine (D14); 2-(Diisopropylamino)ethyl α-phenyl-α-(2-pyridyl)acetate-d14 hydrochloride; α-Phenyl-α-2-pyridylacetic acid 2-(diisopropylamino)ethyl ester-d14 hydrochloride; Spasmolytol-d14 (historical); Pro-Banthine related compound-d14
EINECS	Contact for details

Quality Control

Our Diisopromine-D14 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for isotopic enrichment (D-content), chemical purity, and identity confirmation. We adhere to relevant industry standards for reference materials, and our quality commitment ensures reliable and reproducible performance in your critical assays.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or Certificate of Analysis. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing desiccated under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.