Description

(E)-n-((1H-Indol-3-Yl)Methylene)-3-(2-((4-Chlorobenzyl)Oxy)Phenyl)-1H-Pyrazole-5-Carbohydrazide is a sophisticated heterocyclic compound that serves as a critical pharmacological research intermediate. Its complex molecular architecture, featuring indole, pyrazole, and hydrazide moieties, makes it a valuable scaffold for the development of novel bioactive molecules. This compound is primarily utilized by pharmaceutical R&D and academic research institutions focused on medicinal chemistry and drug discovery programs.

Application

• Medicinal Chemistry Research: Key intermediate for synthesizing and screening novel drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Serves as a core scaffold in the design of potential kinase inhibitors due to its pyrazole-carbohydrazide structure.
• Anticancer Agent Research: Investigated for its potential as a precursor in the development of apoptosis-inducing or anti-proliferative agents.
• Biochemical Probe Synthesis: Used to create specialized probes for studying enzyme function and cellular signaling processes.
• Organic Synthesis Building Block: A versatile intermediate for constructing more complex heterocyclic systems in advanced synthetic chemistry.
• Academic & Institutional R&D: Employed in university and government laboratories for fundamental research in organic and bioorganic chemistry.

Basic Information

Product Name	(E)-n-((1H-Indol-3-Yl)Methylene)-3-(2-((4-Chlorobenzyl)Oxy)Phenyl)-1H-Pyrazole-5-Carbohydrazide
CAS No.	1285502-64-8
Molecular Formula	C26H20ClN5O2
Molecular Weight	470.92 g/mol
Synonyms	(E)-N'-((1H-Indol-3-yl)methylene)-3-(2-((4-chlorobenzyl)oxy)phenyl)-1H-pyrazole-5-carbohydrazide; (E)-N-((1H-Indol-3-yl)methylene)-3-[2-[(4-chlorophenyl)methoxy]phenyl]-1H-pyrazole-5-carbohydrazide; 3-(2-((4-Chlorobenzyl)oxy)phenyl)-1H-pyrazole-5-carboxylic acid (1H-indol-3-ylmethylene)hydrazide; (E)-N'-(1H-Indol-3-ylmethylene)-3-(2-((4-chlorobenzyl)oxy)phenyl)-1H-pyrazole-5-carbohydrazide; CAS 1285502-64-8; Pyrazole-indole carbohydrazide derivative; SCHEMBL23505527
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Quality is verified through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.