Description

(E)-3-(5-Bromothiophen-2-Yl)-n-(4-Nitrobenzylidene)-1H-Pyrazole-5-Carbohydrazide CAS NO 1284280-18-7 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, serving as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D teams and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new small-molecule therapies.
• Agrochemical Development: Serves as a building block for creating new pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Organic Synthesis: Employed in advanced organic synthesis for constructing complex molecules containing pyrazole, thiophene, and hydrazide functionalities.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and functional materials.

Basic Information

Product Name	(E)-3-(5-Bromothiophen-2-Yl)-n-(4-Nitrobenzylidene)-1H-Pyrazole-5-Carbohydrazide
CAS No.	1284280-18-7
Molecular Formula	C15H10BrN5O3S
Molecular Weight	420.24 g/mol
Synonyms	(E)-3-(5-Bromothiophen-2-yl)-N-[(4-nitrophenyl)methylidene]-1H-pyrazole-5-carbohydrazide; 1H-Pyrazole-5-carbohydrazide, 3-(5-bromo-2-thienyl)-N-[(4-nitrophenyl)methylene]-; 3-(5-Bromothiophen-2-yl)-N-(4-nitrobenzylidene)-1H-pyrazole-5-carbohydrazide; (E)-3-(5-Bromothiophen-2-yl)-N-(4-nitrobenzylidene)-1H-pyrazole-5-carbohydrazide; 1284280-18-7; (E)-3-(5-Bromothiophen-2-yl)-N-((4-nitrophenyl)methylene)-1H-pyrazole-5-carbohydrazide
EINECS	Contact for details

Quality Control

Our (E)-3-(5-Bromothiophen-2-Yl)-n-(4-Nitrobenzylidene)-1H-Pyrazole-5-Carbohydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance ensures a reliable supply for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.